Combating and eliminating stomach ulcers will be the aim of these new small molecular robots


To date, the drugs used to treat ulcers and bacterial infectionshave to be administered together with a compound that serves as an inhibitor, which temporarily stops the production of acid in the stomach so that the medicine can do its work without being destroyed . The bad news is that prolonged use of these inhibitors brings with it side effects ranging from headaches to depression and anxiety.

This could be in the past thanks to the development of so-called ' micromotors ', which are small autonomous robots with the thickness of a human hair that serve to administer medicine without using inhibitors, which could be a revolution if approved.

Early results in mice have been successful

These micromotors consist of a spherical magnesium core coated with several able to protect the interior and help to adhere to the walls of the stomach. After swallowing, the nucleus reacts to gastric acid to produce bubbles that serve to propel the robot, a process that also helps reduce acidity. Once the robot is installed in the stomach, the surrounding acidity will begin to fall and at that time the antibiotic will be released.
The research is being conducted by Joseph Wang and Liangfang Zhang of the University of San Diego, who tested mice by giving them five-day doses of antibiotics via micromotors. At the end of treatment they found that the ulcer had disappeared, ie a much more satisfactory response than the use of regular doses of medicine for 20 days.

After 24 hours, the acid levels in the mice's stomachs returned to normal, while the micromotors were dissolved by the same stomach when made of biodegradable materials , all without leaving toxic residues.
These little robots are still in their early days of development , so it will be a few years before we have them playing in our stomachs. Right now, the next thing is to start with studies on larger animals, which will follow the tests in humans, in addition to the corresponding permits and authorizations by the corresponding health bodies.

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